A group of college kids get together for a weekend of booze and war games at an abandoned hospital. The hospital has become the haven for a PTSD stricken war vet coping and acting upon his delusions. Who will survive the game?

Outside the forgotten desert mining town of Darwin, getaway driver Chooch O'Grady is stranded with a busted car and a bag of stolen cash. He's picked up by J.T., a predatory psychopath who murders Chooch and abruptly disposes of the body, leaving signs on the trail. J.T. and his meth-addicted boss, Archie, butt heads over the incident, but the real tension lies with Archie's girlfriend, Rebecca O'Grady. Her affair with J.T. contains false hope that he would be her ticket to freedom. Chooch's murder is all but forgotten until a quiet Stranger shows up looking for the money. Before he can leave behind the isolation that is Darwin, the Stranger must navigate the bizarre ghost town and bring its outlaw inhabitants to justice.

Cassandra, a mute runaway girl, takes refuge in the cemetery in which her mother is laid to rest. She is watched over by Jorge, the cemetery caretaker, an illegal alien who is committed to the restoration of a classic '60 cadillac hearse. Shore is a dynamic, handsome, and brilliant young man who also happens to be homeless. After almost hitting Cassandra in his dilapidated VW bus, he becomes fascinated by the gothic cemetery waif and attempts to befriend her. A sequence of events results in Cass getting lost. Jorge and Shore flee the cemetery in a stolen hearse to find Cassandra before her abusive step-father does. All paths lead to Yermo - the site of a roadside diner and a feisty but compassionate transvestite waitress named Lola.